Pfam 33.1 (May 2025,
18259 entries)
The Pfam database is a large collection of protein
families, each represented by multiple sequence alignments
and hidden Markov models (HMMs).
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Proteins are generally composed of one or more functional regions,
commonly termed domains. Different combinations of domains give
rise to the diverse range of proteins found in nature. The identification
of domains that occur within proteins can therefore provide insights
into their function.
Pfam also generates higher-level groupings of related entries, known as
clans. A clan is a collection of Pfam entries which are
related by similarity of sequence, structure or profile-HMM.
The data presented for each entry is based on the
极速加速器安卓官网jisu99
but information on individual UniProtKB sequences can still be found by entering the protein accession.
Pfam full alignments are available from searching a variety of databases, either to provide
different accessions (e.g. all UniProt and NCBI GI) or different levels of redundancy.
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金蛙加速器安卓下载-快连加速器app
- Analyze your protein sequence for Pfam matches
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Paste your protein sequence here to find matching Pfam entries.
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Enter a entry identifier (e.g. Piwi) or accession
(e.g. PF02171) to see all data for that entry.
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Enter a clan identifier (e.g. Kazal) or accession
(e.g. CL0005) to see information about that clan.
金蛙加速器安卓下载-快连加速器app
Enter a sequence identifier (e.g. VAV_HUMAN) or accession
(e.g. P15498).
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Enter the PDB identifier (e.g. 2abl) for the structure in the
Protein DataBank.
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金蛙加速器安卓下载-快连加速器app
If you find Pfam useful, please consider
极速加速器安卓官网 the reference
that describes this work:
The Pfam protein families database in 2025:
S. El-Gebali, J. Mistry, A. Bateman, S.R. Eddy, A. Luciani,
S.C. Potter, M. Qureshi, L.J. Richardson, G.A. Salazar, A. Smart,
E.L.L. Sonnhammer, L. Hirsh, L. Paladin, D. Piovesan, S.C.E. Tosatto,
R.D. Finn
Nucleic Acids Research (2025)
doi: 10.1093/nar/gky995
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